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GLP- 1 receptor agonists are extremely effective in controlling blood glucose levels because they increase insulin secretion, improve insulin sensitivity, and reduce glucose production in the liver

The medication is administered as a once-weekly subcutaneous injection, with dosing gradually increased to minimize gastrointestinal side effects

Two studies on exenatide 162,166 and one on liraglutide 162 showed no effect of these GLP-1RAs on depression-like behavior

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