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Additionally, GGCT knockdown concomitantly reduced 5- oxoproline (5-OP) levels in MHCC97H cells, consistent with 5-OP being the direct enzymatic product of GGCT activity, and exogenous 5-OP rescued proliferation under Gln-deprived conditions (Fig

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doi: 10.1080/19490976.2022.2038856 Summary Keywords gut microbiota, metabolite, cardiovascular disease, trimethylamine N-oxide, targeted therapy Citation Zhen J, Zhou Z, He M, Han H-X, Lv E-H, Wen P-B, Liu X, Wang Y-T, Cai X-C, Tian J-Q, Zhang M-Y, Xiao L and Kang X-X (2023) The gut microbial metabolite trimethylamine N-oxide and cardiovascular diseases

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