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Targeting this axis may therefore represent a promising strategy to normalize TRP-KYN balance and mitigate depressive symptom burden in MDD

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Metformin or glibenclamide combined with honey (four-week treatment) increased insulin secretion, decreased fructosamine levels and improved hyperglycemia, and reduced creatinine, bilirubin, triglycerides levels, and very low-density lipoprotein cholesterol

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