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7 Self-medication guided by GPs has numerous benefits such as reducing the primary care burden and improving patient empowerment

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10.1038/s41392-022-01004-z 45 GaoM.DongL.YangY.YanJ.LiangY.MaX.et al (2024)

This included a reduction in mRNA levels of Grin2b , Nrxn1 , Cacna1e , and Gabrb2 , as well as the dysregulation of other key genes, such as Reelin , Mecp2 , Tbr1 , and Kenmal

Abnormalities in the sphingolipid metabolism pathway may also contribute to changes in the reactive state of astrocytes, contributing to their pathogenicity in MS in an NFkB-dependent manner (109)