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Tumour fatty acid metabolism in the context of therapy resistance and obesity

A similar finding was observed in mice, in which G6PD overexpression could protect the transgenic mice from oxidative damage and improve their life span through the elevation of NADPH levels, thereby lowering the level of ROS-induced damage (8-OHdG) [110]

Conquer JA, Martin JB, Tummon I, Watson L, Tekpetey F

10.1002/anie.201709183 65 De BruinJ

We chose to focus on biomarkers reported by independent research teams and in multiple tissues to improve the relevance and the strength of evidence, but numerous biomarkers were probably unconfirmed because they have not been evaluated so far by independent team and in several compartments