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Methods: We performed a retrospective cohort study among patients admitted to a large tertiary public hospital in Singapore from January 1-December 31, 2018 with validated ICD-10 codes for cirrhosis

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In the study, researchers at the University of Virginia specifically investigated small-molecule GLP-1 receptor agonists, such as the Food and Drug Administration (FDA)-approved orforglipron, which can be taken orally and are cheaper to produce than their injectable counterparts

Prospective trials specifically enrolling MC4R -deficient patients are urgently needed, with stratification by mutation type - heterozygous vs