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Most individuals regain significant weight once these medications are stopped. Of the participants, 21 were using tirzepatide (Mounjaro and Zepbound), and nine were using semaglutide

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Additionally, a combination of bioflavonoids helps modulate the TGF-, MMP-9/TIMP-1, and GLUT-4-associated pathways in diabetic nephropathy-induced rat models [240]