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The heated electrospray ionization source was operated at 375 C and 2 or 3.5 kV for negative and positive ion modes, respectively

This distinction matters because traditional caloric restriction often results in muscle loss alongside fat loss, which can lower metabolic rate and make weight maintenance challenging

If you have not yet tried the maximum 2.4mg dose of semaglutide, it may be worth maximizing that dose first before switching

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