Complement factor H (CFH) is a crucial regulator of the alternative pathway within the complement system, inhibiting the activity of the C5 converting enzyme, reducing C5 cleavage, and exerting anti-inflammatory effects (81)
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Its activation enhances the conversion of Gln to glutamate and promotes subsequent GSH synthesis, while also leading to ROS accumulation, which inhibits the proliferation of lung cancer cells and promotes apoptosis (46)
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Triglycerides can drop substantially, with reductions of 20 to 30% commonly reported in clinical settings