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10.1038/s41419-018-1152-2 231 WeiQ.DongG.YangT.MegyesiJ.PriceP
This route however appears to be largely ignored and probably will continue to be ignored, since the strategy so far has been to simply create agonists which are structurally designed to be resistant to DPP-4 (In fact, most modifications to extend the half-life of GLP1R/GIPR/GR agonists so far, do so by making the drugs resistant to DPP-4 )
Multiple squamous cell carcinomas of the oral cavity in a young patient with graft-versus-host disease following allogenic bone marrow transplantation
But they require completely different innovation approaches
Do not use GLP-1 if you are pregnant or breastfeeding, or planning to become pregnant or breastfeed
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