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The trial also showed statistically significant reductions in key obesity-related risk factors

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This does not indicate degradation

In phase 2 clinical trials, people with obesity who used MariTide achieved up to 20% weight loss after one year, along with significant improvements in blood sugar levels and other metabolic markers

Both kidneys and canal systems and confluence of the inferior caval vein to the right heart demonstrated that the trapped blood volume is rapidly redistributed (Vukojevic et al., 2018)