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Multiple uremic toxins have been identified as inducers of eryptosis, including indoxyl sulfate (IS) (Voelkl et al., 2013), acrolein (Fller et al., 2008b), and indole-3-acetic acid (IAA) (Gao et al., 2015) as listed in Table 1

[5] FDA labeling information for Xultophy

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They had a body mass index (BMI) of at least 30 on the date of treatment initiation or during the latest available primary care visit, or a BMI of at least 27 with one or more weight-related comorbidities such as hypertension, dyslipidemia, obstructive sleep apnea or cardiovascular disease