can glp 1 increase cholesterol Anti-atherosclerotic effects of the glucagon-like peptide-1 (GLP-1) based therapies in patients with type 2 Diabetes Mellitus: A meta-analysis Does GLP-1 Help Lower Cholesterol?

in Spain, its current prevalence ranges between 2833%11,12 and it is a recognized as a cardiovascular risk factor and increases the mortality in this population.1315 Furthermore, in patients with DM2 and advanced CKD there are limitations in the prescription of certain antihyperglycemic drugs (e.g., metformin or sulfonylureas) and there is an increased risk of hypoglycemia with antihyperglycemic treatment,16 a complication that is associated with increased cardiovascular risk17 and hinders the achievement of glycemic control targets

Food-based sources work too, but only if you are eating enough

PLoS One 11 (6), e0157509e0157514

Therefore, the stronger the affinity to albumin the smaller the free and active circulating fraction of the GLP-1 peptide

These physiological changes occur regardless of exercise frequency, making caloric deficit achievable through dietary adjustment alone in many patients, though long-term outcomes may be optimized with some movement