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Relative metabolite abundance was calculated as the percentage of the total metabolite pool

c-Myc also regulates several key EMP enzymes, including Glut1, PKM2, and LDHA [74], increasing tumor cell uptake of glucose and production of pyruvate

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Exendin-4 also promotes the polarization of bone marrow-derived macrophages in mice towards the M2 subtype by modulating the STAT3 pathway and cAMP protein kinase A (PKA) signaling [91, 92]

This study provides evidence that exposure of isolated fresh erythrocytes for 24 h to CSE induces eryptosis by p38 MAPK-initiated DISC formation, followed by activation of caspase-8/caspase-3 via ceramide formation by neutral SMase