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It is contraindicated in people with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

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Cardiovascular Effects Additionally, semaglutide has demonstrated cardioprotective effects independent of glucose lowering, possibly through anti-inflammatory mechanisms, improved endothelial function, and favorable effects on blood pressure and lipid metabolism

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Follow-up appointments allow healthcare providers to adjust the dosage if needed