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This enzyme wastes a helpful molecule called nicotinamide (a form of vitamin B3) by turning it into something useless instead of recycling it into NAD+, think of NAD+ as the main battery fuel that powers your cells energy factories (mitochondria)

Elevated mean cell volume (MCV) and homocysteine levels may indicate a vitamin B12 deficiency

As the name implies, hepcidins are predominantly expressed in the liver, but they are also found in much smaller amounts in the heart, brain, lung [154], and body fluids like urine [156]