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Kinetics parameters The K m value for GSH was obtained by reacting about 0.5 g of purified mammalian e-GSTs with variable amounts of GSH (from 0.02 to 2 mM) in the presence of 1 mM CDNB, in 0.1 M potassium phosphate buffer, pH 6.5 (25 C)

Post-trial follow-up data from EMPA-KIDNEY suggest that cardiorenal benefits may persisted for up to 1 year after treatment cessation, highlighting the importance of continued therapy for long-term effectiveness [117]

Every glutathione IV preparation prescribed in clinical practice is compounded, and as with any compounded preparation, it has not been reviewed by the FDA for safety or efficacy in these uses