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Previous studies on ferroptosis have found that ferroptosis is involved in a variety of pathological processes, such as tumors [9, 10], ischemia-reperfusion injury [11, 12], and other degenerative diseases [13] associated with extensive lipid peroxidation

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To examine the importance of this process, we took advantage of the potent GR inhibitor 2-AAPA (46), commonly used at 25 M (47)