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Molecular architecture of bacterial amyloids in Bacillus biofilms

The compound demonstrates exceptional target selectivity, with no inhibition of related methyltransferases (DNMT1, PRMT3, COMT) or NAD+ salvage enzymes (NAMPT, SIRT1) at concentrations up to 600 M

This screen identified the hexanoic N-terminal substituent as the most active compound

Understanding proper peptide reconstitution and correct storage practices is essential for minimizing variability-related side effects