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Fridman, W

GLUD1mediated production of alpha-ketoglutarate (-KG) and the accumulation of ROS trigger migration and invasion by inducing the expression of Snail (25)

CD4 + CD25 + FOXP3+) normally suppress autoreactive lymphocytes, but in HT, both their number and suppressive function are reduced, correlating with disease severity (Chen et al., 2023)

Incretin therapies: Highlighting common features and differences in the modes of action of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors

Escalation reduces side effects The comparison between the 4mg escalated and 4mg non-escalated cohorts provides critical insight into dosing strategy