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Research shows men losing 10%+ of body weight experience measurable gains in testosterone and sperm motility within 6 to 12 months

It is notoriously resistant to diet, exercise, and bariatric surgery

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However, it was discontinued due to ineffectiveness

The expression of ZO-1, Occludin, SIRT1, STAT3, p-STAT3, RORt, IL-6, IL-1, TNF-, and -actin was examined using the method previously described ( 2.14 Statistical analysis Data are presented as the mean standard deviation