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Across the study: Patients on the highest dose had a 75.8% reduction in knee pain More than 12% reported being completely pain-free Over two-thirds experienced at least a 70% improvement Systolic blood pressure dropped by 14 mmHg , an additional cardiovascular benefit For people with obesity who struggle with daily movement or have been told they may eventually need a knee replacement, these improvements could be life-changing

Treatment is provided only after an in-person medical evaluation confirming clinical appropriateness

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Exploring additional biomarkers will likely become a key focus in future clinical trials to accurately select patients with low risk of local recurrence and further stratify these already low-risk individuals