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Compassionate Use Programs Compassionate use (or expanded access) is a regulatory pathway that allows the use of an investigational drug outside of a clinical trial for patients with a serious or immediately life-threatening condition who have no comparable treatment options

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Surprisingly, patients on these lower doses experienced weight loss comparable to those on the full dose of 3.0 mg, with average weight reductions of 7.4, 7.8, 9.0 and 8.0 kg for dosages of 1.2, 1.8, 2.4 and 3.0 mg, respectively (130)

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