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Summary Integrating emerging mechanistic and clinical observations, this review synthesizes current evidence from a metabolic flux perspective
Brownlee RD, Kass PH, Sammak RL
16.667 / Dihexa, 500 30 , , 15 , 0,5 ,
Diabetologia 53 , 153159 (2010)
Based on accumulating evidence from large randomised controlled trials (RCTs), we hypothesised that treatment with sodiumglucose cotransporter 2 (SGLT2) inhibitors is associated with significant reductions in MACE, including cardiovascular death, non-fatal MI, and non-fatal stroke, as well as decreased rates of hospitalisation for heart failure
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