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Step 2 Starting Dose and Titration: Tirzepatide starts at 2.5mg weekly for 4 weeks, then increases by 2.5mg every 4 weeks through 5mg, 7.5mg, 10mg, 12.5mg to the maximum 15mg dose

Department of Health and Human Services Physical Activity Guidelines recommend at least 150-300 minutes of moderate-intensity aerobic activity weekly, along with muscle-strengthening activities on 2 or more days per week