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The FDA declared the tirzepatide shortage resolved in late 2024 and the semaglutide shortage resolved in early 2025, and the grace periods for winding down compounding ended around May 2025

This meta-analysis evaluates the weight loss effects of GLP-1 receptor agonists, including Semaglutide, underscoring the potential benefits for overweight or obese individuals with IBS, where weight management can play a role in symptom relief

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