Manufacturing processes, quality control standards, and delivery mechanisms also differ
With obesity rates in the UK now at very high levels, and associated with substantial multimorbidity, additional treatment options for sustained weight loss are greatly needed. Jason Murphy, the head of pharmacy at Chemist4U, said the announcement was a major step forward in treating obesity, increasing access and enabling millions more people to get treatment
These side effects were typically present while participants were gradually increasing their dose in the first few weeks of the trial and tended to improve thereafter
Real-world data from a 2025 study in Diabetes, Obesity and Metabolism which looked at actual clinical patients rather than trial participants showed tirzepatide patients lost 5.3% of body weight over six months compared to 2.7% with semaglutide
They affect every aspect of what you are injecting