95% CI, 1.27-1.87)
A good clinician should review your health history, explain options clearly, discuss side effects, and help you understand what realistic progress may look like over time
Specifically, in women who are postmenopausal, exogenous estrogen causes homocysteine levels to drop, but prior to menopause, excess estrogen may increase homocysteine.[ref][ref] Both high and low homocysteine levels increase all-cause mortality, with the caveat that the increase in mortality risk is only seen if homocysteine is not low due to vitamin intake
Two, people with genuine B12 deficiency are, after withdrawal, at risk of developing worse symptoms, which may even persist after resuming treatment
The question of can you use expired semaglutide comes up often, and while the peptide does not become dangerous, it does become progressively less effective