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1/Smad2/3 axis, a key pathway in fibrosis and epithelial-mesenchymal transition, thus reducing tissue fibrosis and promoting regenerative over fibrotic repair 4

Mrquez J, Alonso FJ, Mats JM, Segura JA, Martn-Rufin M, Campos-Sandoval JA

Punicalagin from pomegranate ameliorates TNF-/IFN--induced inflammatory responses in HaCaT cells via regulation of SIRT1/STAT3 axis and Nrf2/HO-1 signaling pathway

46 In a simulative binding model of GIP and the receptor, the fragment from position 3142 neither interacted with the receptor, nor formed any specific structure, but it was able to cling to the receptor