Insulin resistance promotes Parkinsons disease through aberrant expression of alpha-synuclein, mitochondrial dysfunction, and deregulation of the Polo-like Kinase 2 signaling
The findings highlight an opportunity to increase use of GLP-1s for weight and disease management and, in doing so, increase access to GLP-1s among adults who smoke, Kristy A
In December 2024, Gubra A/S , a company that specializes in pre-clinical contract research and peptide-based medication discovery for metabolic and fibrotic illnesses, has announced a collaboration with Amylyx Pharmaceuticals, Inc
Research suggests it may have potential for tissue development and compositional changes
The study showed significant decreases in HOMA2-B scores, proinsulin/insulin ratios, and proinsulin/C-peptide ratios in both tirzepatide (all doses) and dulaglutide compared to placebo [66]