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Description

The Cox proportional hazards model was used to calculated adjusted hazard ratios (aHRs) with 95% confidence intervals (CIs) for outcomes associated with the use of GLP-1 RAs

The most consistent and comparable endpoints remain weight loss and the associated reduction in lipotoxic load

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Results of Phase 2 trials have demonstrated that dulaglutide causes significant, dose-dependent reductions in HbA1c levels, with up to a 1.5% decrease observed after 12 weeks of treatment with a 1.5 mg dose