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[3] A separate Japanese clinical trial showed something even more interesting
Lin JH, Liu CC, Liu CY, Hsu TW, Yeh YC, How CK, et al
The non-GLP-1 alternatives matter for patients who cannot tolerate GLP-1s or do not meet eligibility, a unique hedge
Contraindications:: Patients with a personal or family history of medullary thyroid carcinoma (based upon animal data - see FDA Warning) History of hypersensitivity to semaglutide or any of its excipients (serious reactions including angioedema & anaphylaxis have been reported) Side Effects: GI Adverse events: nausea, vomiting, constipation, diarrhea (~5-15%) most GI side side effects occur during dose initiation or escalation and wane after a few weeks (Drucker, 2024)
Vitamin B12 is measured in micrograms (mcg) , with a standard dose of 1,000 mcg per injection
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