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It is best to view supplementation as a way to "fill the gap" alongside a nutrient-dense diet

In parallel, advances in NP engineering have enabled therapeutic or diagnostic cargo to be delivered across physiological barriers with high specificity, potentially improving pharmacokinetics, bioavailability, and plasma half-life by shielding payloads from enzymatic degradation and enabling sustained release [16]

Carbon monoxide (CO) levels in exhaled breath condensate were also higher in AR patients (137, 138)

A., Himmerich H

This dual modulation suggests curcumin may optimize physiological stress responses when administered as a nutritional supplement