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GLP-1s have also been studied as a possible treatment medication for AUD

From the earliest animal-derived exenatide to the human-derived GLP-1RA liraglutide, GLP-1RA has undergone short-acting, long-acting, weekly preparations and oral preparations, similar to the development of insulin analogs

More serious but rare adverse events include pancreatitis, gallbladder disease, and thyroid C-cell tumours (patients should be advised to report symptoms such as neck mass, dysphagia or persistent hoarseness)

Research Priorities Future investigations should concentrate on a few crucial areas

This situation became further unclear in 1948 when Earl Sutherland and Christan De Duve, two biochemists at Washington University School of Medicine in St Louis, detected glucagon in gastric extracts (Holst 1983