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Why is alpha-lipoic acid included?+ Alpha-lipoic acid (thioctic acid) is unusual in being both water- and lipid-soluble, so it can act in any part of the cell

Targeting RAAS components with inhibitors such as ACE inhibitors, angiotensin-receptor blockers and aldosterone antagonists can mitigate these pro-inflammatory effects and improve outcomes

Ketamine reduces inflammation-induced QA elevations, with QA reductions correlating with symptom improvement, and KYNA/QA ratios have been shown to predict ketamine responsiveness, linking KP modulation to clinical outcomes [205, 206]

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Exp Toxic Pathol 49, 197200