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Melatonin is often referred to as the body's "sleep hormone," though it is more accurately described as a circadian signaling molecule that helps synchronize the sleep-wake cycle with environmental light and darkness and promotes sleep onset partly by lowering core body temperature

Experts advise patients taking semaglutide or considering treatment to discuss the risks and benefits with their doctors, especially those with other optic nerve issues such as glaucoma or preexisting visual loss

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Prior evidence of obesity was common (83.9%), and an additional 8.2% had both obesity and type 2 diabetes