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A small subset of "sentinel" participants is dosed first, before the rest of the cohort, as an additional safeguard

Seiwerth S, Sikiric P, Grabarevic Z, Zoricic I, Hanzevacki M, Ljubanovic D, Coric V, Konjevoda P, Petek M, Rucman R, Turkovic B, Perovic D, Mikus D, Jandrijevic S, Medvidovic M, Tadic T, Romac B, Kos J, Peric J, Kolega Z

Do not spray the liquid directly onto the powder puck

Mechanism of Action: Why These Peptides Complement Each Other AOD-9604 functions as a synthetic analogue of the C-terminal fragment of human growth hormone (amino acids 176-191), retaining the lipolytic properties of hGH without triggering the insulin resistance or hyperglycaemia associated with full-length hormone administration

European Journal of Endocrinology, 1998