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Symptoms appear within the first few weeks, peak during weeks 6-8 (coinciding with dose escalation), and resolve substantially by week 12

While results vary, substantial benefits are seen over weeks of consistent treatment

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[5] proved that GIP, originally named gastric inhibitory polypeptide, could explain this incretin effect by inducing glucose-stimulated insulin secretion, and renamed the peptide as glucose-dependent insulinotropic polypeptide. Following the identification of GIP, the search for insulinotropic incretins persevered

Lifestyle and Sun Exposure Excessive sun exposure, smoking, poor diet, and lack of sleep can slow down results