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Consequently, GST activity reduction leads to the accumulation of ROS in inflamed lesions, as it was reported in psoriatic plaques, where ROS levels are 3-fold higher than in non-lesioned skin (64)

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In addition, vascular endothelial growth factor increases H 2 S level by upregulating CSE expression in endothelial cells, thereby promoting angiogenesis of endothelial cells obtained from breast carcinomas (B-TECs) (29)

Cataracts: Because glutathione is an essential antioxidant in the lens, boosting GSH levels with NAC supplementation may be utilised to prevent cataract risk [12]

Anti-Inflammatory- May help modulate inflammatory pathways, providing potential relief from conditions associated with chronic inflammation