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As oxidative stress increases, further stimulation of pro-inflammatory cytokines such as TNF- and IL-1 increases and contributes to synaptic dysfunction and neuronal degeneration (Dawi et al., 2024)

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Still, revenue is expected to climb to $1.17 trillion from $1.07 trillion

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Historically, this increased insulin response mediated by GLP-1 and GIP had been attributed to factors termed incretins (derived from incretion, a term used at that time to refer to a secretion that remains inside the body), hence the name incretin effect is still used today to describe the rise in insulin mediated by the action of these hormones