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J Biol Chem 280 , 3376633774, doi: 10.1074/jbc.M504604200 (2005)

48 Muscle Loss: Significant weight loss can sometimes include loss of muscle mass, which further slows metabolism

Itemizing deductions only makes sense if your tax write-offs are higher than the standard deduction and about 90% of taxpayers take the standard deduction instead of itemizing

Downstream observations in models include transcriptional changes consistent with enhanced mitochondrial function and lipid utilization