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Benefits were more pronounced in studies using 6001,200mg per day over at least eight weeks.2 A 2022 randomized controlled trial in patients with metabolic syndrome found that 600mg of ALA daily for 12 weeks significantly reduced triglyceride levels and total cholesterol compared to placebo.59 However, the study did not observe significant changes in LDL-C or HDL-C

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[29] The thiol group also has a high affinity for heavy metals, so that proteins containing cysteine, such as metallothionein, will bind metals such as mercury, lead, and cadmium tightly