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Novos message here is clear: Wegovy can still compete

But more studies are needed to understand the finding

Unlike metformin, which has a well-established association with vitamin B12 malabsorption through interference with calcium-dependent B12-intrinsic factor complex absorption in the terminal ileum, there is no official link between GLP-1 receptor agonists and direct B12 depletion

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Persistent nausea can create a general sense of malaise that patients describe as fatigue, while the physical effects of frequent vomiting or diarrhea can cause legitimate exhaustion