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GLP-1 medications can reduce appetite so effectively that some patients inadvertently under-eat and under-drink, leading to dehydration and electrolyte imbalances

Additionally, because NAD+ supports metabolic pathways, some practitioners recommend taking a methyl donor supplement (such as TMG, trimethylglycine) concurrently, to aid in processing any excess nicotinamide produced

Economic preference or convenience does not qualify as lawful justification for compounding

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