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Triggers include genetic susceptibility (HLA-DR3/DR4) and environmental factors (viral infections, gut microbiome alterations)

In certain instances, when an auris formulation or composition is administered via intratympanic injection, a reduced frequency of administration alleviates discomfort caused by multiple intratympanic injections in individuals undergoing treatment for a middle and/or inner ear disease, disorder or condition

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Author contributions MW: Data curation, Investigation, Writing original draft, Writing review & editing

It works by dramatically reducing the size and output of the skin's sebaceous glands (the glands that produce oil), slowing down skin cell production inside the pore, and killing the bacteria that contribute to acne