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For OTA, the Klaassen equation has been used to estimate the continuous exposure to OTA based on blood plasma concentrations, and assumptions for plasma clearance and bioavailability (details in Duarte et al

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While this study is small, they wrote, we provide essential preliminary data for the design and development of larger randomized control trials. Those trials are already underway, testing GLP-1 therapy for various substance use disorders, including alcohol and opioids

In other populations, were going to see iron overload, as we already do, actually