k , Bodipy-C11 581/591 flow cytometry of cells treated with Fento-1 (24 h) and inhibitors used 2 h prior
However, when excess free Fe 2+ is present in the cell, ferritin is recruited and solubilized by specific cargo receptor recognition, and the released excess Fe 2+ in turn increases the formation of hydroxyl radicals through the Fenton reaction, inducing reactive oxygen species (ROS) production and increased susceptibility to cellular ferroptosis ( FIGURE 1 Lipid peroxidation is an important factor driving ferroptosis
doi: 10.1016/j.mad.2018.03.013 13 KotsantisPPetermannEBoultonSJ
Takeda T, Azumi J, Masaki M, Nagasawa T, Shimada Y, Aso H, et al
Q:What is the delivery time