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The aim of this review is therefore to forward an enhanced form of various microbial theories of AD into a collective and integrative umbrella term of microbial AD denoted as MAD. The evidence we present focuses on the notable similarity of the key AD proteins and peptides regarding their primary or alternative functions as antimicrobial agents

Its cost/benefit as a fertility treatment is also tenuous given the alternatives

When designing dose-escalation studies, establish three or four dosing tiers to identify threshold and saturation effects

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