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Safety and translational considerations were discussed, including brain penetration after systemic administration

Haakinson DJ, Leeds SG, Dueck AC, Gray RJ, Wasif N, Stucky CC et al

CFS involves fatigue for at least six months and at least four to six accompanying symptoms, such as increased tiredness after exertion, sleep disturbance, muscle and joint pain, head and neck pain, cognitive impairment, orthostatic disturbances, and marked restriction of everyday activities not attributable to any other specific disease

While the name is widely recognised within peptide research communities, it does not refer to a distinct molecule or independently studied peptide

IGF-1 LR3 stands for Insulin-like Growth Factor 1 Long Arg3 a synthetic version of the naturally occurring IGF-1 peptide