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According to the MHRA/EMC SmPC, these include: Nausea (very common) Vomiting (very common) Diarrhoea (very common) Abdominal pain (common) Constipation (common) Dyspepsia/indigestion (common) Belching/eructation (common) These effects are typically dose-dependent and most pronounced during treatment initiation or dose escalation

Most compounded semaglutide can tolerate brief periods at room temperature, typically limited time unrefrigerated , but extended exposure begins breaking down the peptide

Comprehensive Psychiatry, 53(2), 181-186

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Compounded semaglutide injection from PlexusDx contains the same active ingredient as Wegovy and uses identical injection mechanics, so discomfort profiles are comparable